Personal Description | Dr. Nicolas VIPHAKONE

Personal Description

pict N. Viphakone

           I am a naturally curious and open-minded person and I have always had an interest in everything that the universe has to offer to our senses. As a consequence, I have always had a strong interest in Science. During high school, I developed a particular interest in biology.

           After various voluntary laboratory-training periods during my undergraduate studies at the University of Bordeaux, I started to be involved in scientific research in 2002 in the group of Dr Lionel Minvielle-Sebastia (IBGC, Bordeaux, France) for my master degree. At that time, his group was studying 3'-end processing of eukaryotic RNAs in yeast and this topic matched my growing interest in the mechanisms driving gene expression. During this period, I developed my experimental skills in biochemistry and molecular biology in relation to mRNA metabolism in the eukaryotic model organism S. cerevisiae. Then, in the same research group, I undertook a PhD in cellular biochemistry and molecular biology during which I studied pre-mRNA 3'-end processing in yeast and its regulation by non-canonical poly(A)-binding proteins (ncPAB).

       With the aim to continue working on gene expression but in higher eukaryotes, I moved to the UK in 2008 for a postdoctoral position in the group of Prof. Stuart Wilson (MBBThe University of Sheffield). Since then, I have been working on the molecular mechanisms allowing mRNA transport from the nucleus to the cytoplasm in human cells using a wide range of techniques in molecular biology, cell biology and biochemistry.

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